It is primarily used as an ion-pairing reagent in reversed-phase HPLC to improve the retention and separation of polar, ionic, and basic compounds.
1-Octane sulfonic acid sodium salt (Anhydrous) HPLC Grade | CAS: 5324-84-5 | MF: C8H17O3SNa | MW: 216.28, Buy now for accurate and reproducible results from LiChrom Ion-Pair Reagent.
1-Octane Sulfonic Acid Sodium Salt Anhydrous HPLC Grade (CAS No. 5324-84-5) is a chromatography-grade ion-pairing reagent that is used to high-resolution peptides and proteins separation. This compound is provided as a white crystalline solid with molecular formula C8H17O3SNa and is very soluble in water and methanol. This reagent, also known as Sodium 1-Octanesulfonate, is very common in reversed-phase HPLC to increase the retention and separation of charged biomolecules.
Applications
- LiChrom 1-Octane Sulfonic Acid Sodium Salt Anhydrous HPLC is mostly used in HPLC analysis of peptides and proteins, where ionic interactions are of crucial interest to determine the separation efficiency.
- It is also used as a mobile phase in pharmaceutical and biochemical analyses, which offers consistent retention behavior by analytical run.
- Moreover, the reagent is also applicable in the preparation of HPLC buffers to be used in neurochemical studies to aid in the proper quantification of neurotransmitters.
- The next notable use is that it is being used as a buffer additive in procedures that seek to quantify L-Dopa levels and the use of ion-association reagent in customary examination procedures.
Key Features
- HPLC-Grade Purity: Allows low noise baselines and accurate peak integration.
- Efficient Ion-Pairing: Enhances peptide and protein resolution in the chromatography.
- High Solubility: Allows the mobile phases and buffers to be prepared quickly.
- Batch-to-Batch Consistency: Appropriate to proven analysis techniques.
General Overview
LiChrom ion-pair reagents have been designed to satisfy the needs of progressive separation science. This product is consistent in its performance, chemical stability, and easy to use thus suitable in the development of methods, routine analyzes and regulated lab conditions.
Select LiChrom, which has ion-pair reagents designed to achieve accuracy, resolution and reliable chromatographic results.
About Brand
LiChrom products are designed specifically for Liquid Chromatography. LiChrom products exceed the rigorous requirement of HPLC analysis in various industries. Apart from HPLC- solvents, the LiChrom series encompasses HPLC-grade buffer salts, and HPLC ion pair reagents. These products provide the highest levels of accuracy and precision, as well as reproducibility of results,ensuring that your chromatography requirements will be met.
Frequently Asked Questions
It interacts with oppositely charged analytes and enhances their interaction with the stationary phase, supporting improved retention, peak characteristics, and chromatographic resolution.
HPLC Grade material typically provides an assay of 99% or higher, depending on the product specification.
It is used in pharmaceutical analysis, peptide and protein separation, amino acid analysis, impurity profiling, and determination of charged organic compounds by HPLC and UPLC.
HPLC Grade ion-pair reagents provide controlled purity and low impurity levels, supporting reduced background interference, improved reproducibility, and reliable analytical performance.
Yes. It is readily soluble in water and is suitable for preparing aqueous mobile phases and buffer systems for ion-pair chromatography.
It interacts with charged analytes and increases their retention on reversed-phase columns, supporting improved selectivity, resolution, peak characteristics, and retention consistency.
The anhydrous form contains no water of crystallization, supporting accurate weighing, concentration calculations, and consistent mobile-phase preparation.
Store the product in a tightly sealed container in a cool, dry environment protected from moisture and contamination.
It is used in pharmaceutical, biotechnology, chemical, environmental, academic research, and analytical testing laboratories performing ion-pair chromatography.
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